Abstract

3.Tobacco smoke affect on Haematological parameters and the protective role of vitamin E in albino rats
Rafat Khan
Tobacco smoke is a well-known environmental toxin with adverse systemic effects, including hematological disturbances. This study investigates the impact of tobacco smoke exposure and the role of vitamin E on key hematological parameters viz. Erythrocyte Sedimentation rate (ESR), Packed cell volume (PCV), Hemoglobin concentration (Hb conc.) and Red blood cell (RBC) counts in albino rats. The albino rats were divided into three sets (A, B and C) having ten (10) rats in each. Additionally, the study evaluates the potential ameliorative role of Vitamin E, a powerful antioxidant, in mitigating the hematological alterations induced by tobacco smoke. The outcome of present investigation shows that tobacco smoke significantly impairs hematological parameters, while Vitamin E supplementation exhibits protective impacts due to its anti-oxidative properties. Keywords: Cigarette smoke, Vitamin E, Hematological parameters and albino rat.